PHARMACEUTICAL ORGANIC CHEMISTRY -II (Practical)

 BP305P. PHARMACEUTICAL ORGANIC CHEMISTRY -II (Practical)

I. Experiments involving laboratory techniques 

 Recrystallization

 Steam distillation

II. Determination of following oil values (including standardization of reagents)

 Acid value 

 Saponification value 

 Iodine value

III. Preparation of compounds

 Benzanilide/Phenyl benzoate/Acetanilide from Aniline/ Phenol/Aniline by acylation reaction. 

 2,4,6-Tribromo aniline/Para bromo acetanilide from Aniline/ 

 Acetanilide by halogenation (Bromination) reaction. 

 5-Nitro salicylic acid/Meta di nitro benzene from Salicylic acid /Nitro benzene by nitration reaction. 

 Benzoic acid from Benzyl chloride by oxidation reaction. 

 Benzoic acid/ Salicylic acid from alkyl benzoate/ alkyl salicylate by hydrolysis reaction. 

 1-Phenyl azo-2-napthol from Aniline by diazotization and coupling reactions. 

 Benzil from Benzoin by oxidation reaction. 

 Dibenzal acetone from Benzaldehyde by Claison Schmidt reaction

 Cinnammic acid from Benzaldehyde by Perkin reaction

 P-Iodo benzoic acid from P-amino benzoic acid

Recommended Books (Latest Editions)

1. Organic Chemistry by Morrison and Boyd

2. Organic Chemistry by I.L. Finar , Volume-I

3. Textbook of Organic Chemistry by B.S. Bahl & Arun Bahl.

4. Organic Chemistry by P.L.Soni

5. Practical Organic Chemistry by Mann and Saunders.

6. Vogel’s text book of Practical Organic Chemistry

7. Advanced Practical organic chemistry by N.K.Vishnoi.

8. Introduction to Organic Laboratory techniques by Pavia, Lampman and Kriz.