MEDICINAL CHEMISTRY – I (Practical) syllabus

 BP406P. MEDICINAL CHEMISTRY – I (Practical)

I Preparation of drugs/ intermediates

1 1,3-pyrazole

2 1,3-oxazole

3 Benzimidazole

4 Benztriazole

5 2,3- diphenyl quinoxaline

6 Benzocaine

7 Phenytoin

8 Phenothiazine

9 Barbiturate

II Assay of drugs

1 Chlorpromazine

2 Phenobarbitone

3 Atropine

4 Ibuprofen

5 Aspirin

6 Furosemide

III Determination of Partition coefficient for any two drugs

Recommended Books (Latest Editions)

1. Wilson and Giswold’s Organic medicinal and Pharmaceutical Chemistry. 

2. Foye’s Principles of Medicinal Chemistry. 3. Burger’s Medicinal Chemistry, Vol I to IV. 4. Introduction to principles of drug design- Smith and Williams.

5. Remington’s Pharmaceutical Sciences.

6. Martindale’s extra pharmacopoeia.

7. Organic Chemistry by I.L. Finar, Vol. II. 

8. The Organic Chemistry of Drug Synthesis by Lednicer, Vol. 1-5.

9. Indian Pharmacopoeia. 

10. Text book of practical organic chemistry- A.I.Vogel.